Search results for "Geiller–Seifter procedure"

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Acetaldehyde as a drug of abuse: insight into AM281 administration on operant-conflict paradigm in rats

2013

Increasing evidence focuses on acetaldehyde (ACD) as the mediator of the rewarding and motivational properties of ethanol. Indeed, ACD stimulates dopamine release in the nucleus accumbens and it is self-administered under different conditions. Besides the dopaminergic transmission, the endocannabinoid system has been reported to play an important role in ethanol central effects, modulating primary alcohol rewarding effect, drug-seeking and relapse behaviour. Drug motivational properties are highlighted in operant paradigms which include response-contingent punishment, a behavioural equivalent of compulsive drug use despite adverse consequences. The aim of this study was thus to characterize…

Cannabinoid receptorPunishment (psychology)media_common.quotation_subjectCognitive NeuroscienceNucleus accumbenslcsh:RC321-571Behavioral NeuroscienceDopamineCB1 AntagonistmedicineOriginal Research ArticleGeiller-Seifter procedurelcsh:Neurosciences. Biological psychiatry. Neuropsychiatrymedia_commonrelapseAddictionDopaminergicExtinction (psychology)Endocannabinoid systemGeiller–Seifter procedureNeuropsychology and Physiological PsychologyCB1 receptor blockade/antagonismSettore BIO/14 - FarmacologiaAcetaldehyde Lever pressing relapse Geiller-Seifter procedure CB1 receptor blockade/antagonismPsychologyNeurosciencepsychological phenomena and processesmedicine.drugNeuroscienceacetaldehydelever pressingFrontiers in Behavioral Neuroscience
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